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Zoekresultaten - 63 results
A Transcriptomic Biomarker to Classify Chemical-Induced Histone Deacetylase Inhibition in Human HepaRGTM Cells
Publication Type: Scientific poster, presentation or proceeding Authors: Julie Buick; Eunnara Cho; Anouck Thienpont; Birgit Mertens; Andrew Williams; Carole Yauk; Matthew Meier Source: Health Canada ...
Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake
Publication Type: Scientific poster, presentation or proceeding Authors: Sivakumar Murugadoss; Alexandra Schaffert; Ronette Gehring; Tom Roos; Nunzia Linzalone; Gabriele Donzelli; Martin Paparella; ...
Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals
Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Matthew Meier; Carole Yauk; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens ...
Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake
Publication Type: Scientific poster, presentation or proceeding Authors: Sivakumar Murugadoss; Alexandra Schaffert; Ronette Gehring; Tom Roos; Nunzia Linzalone; Gabriele Donzelli; Martin Paparella; ...
Reducing the Burden on Animals and the Heart: An Evidence-Based Approach to Cardiotoxicity Assessment
Publication Type: Scientific poster, presentation or proceeding Authors: Alexandra Schaffert; Sivakumar Murugadoss; Birgit Mertens; Tom Roos; Ronette Gehring; Nunzia Linzalone; Gabriele Donzelli; ...
A Systematic Review on Pollutant Induced Cardiotoxicity: Providing a Toxicological Foundation for NAM Development and Regulatory Acceptance
Publication Type: Scientific poster, presentation or proceeding Authors: T. Roos; C. Leenaars; A. Schaffert; M. Paparella; S. Murugadoss; Birgit Mertens; N. Linzalone; G. Donzelli; M. ...
Mixtures of genotoxicants: does the principle of additivity apply?
Publication Type: Scientific poster, presentation or proceeding Authors: Julie Sanders; Roel Anthonissen; George Johnson; Tamara Vanhaecke; Birgit Mertens Source: EEMGS meeting, Malaga, Spain (2023) ...
The GENOMARK transcriptomic biomarker demonstrates a high predictivity for genotoxic hazards and utility in potency ranking in human HepaRGTM cells
Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Eunnara Cho; Andrew Williams; Matthew Meier; Carole Yauk; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens ...
Development of an AOP-based IATA for genotoxicity
Publication Type: Scientific poster, presentation or proceeding Authors: E Demuynck; T Vanhaecke; A Thienpont; V Rogiers; LMT Winkelman; JB Beltman; A Reus; F Macron; C Bossa; A Peijnenburg; ...
The GENOMARK biomarker inhuman HepaRGTM cells: a new approach methodology for genotoxicity assessment
Publication Type: Scientific poster, presentation or proceeding Authors: Anouck Thienpont; Stefaan Verhulst; Leo van Grunsven; Vera Rogiers; Tamara Vanhaecke; Birgit Mertens Source: ...