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In Silico Methods for Chromosome Damage.
endpoint in each regulatory setting with respect to human health, including for pharmaceuticals. To this extent, a compound potential to induce gene mutations as well as chromosome damage needs to be ...
In vitro model to study the endocrine disrupting activity of migration products from plastic food contact materials
(these) activity(ies) will be explored using cell based transactivational assays also named “reporter gene assays. The MCF7 recombinant cells used here are genitically modified cells containing the firefly ...
Testing chemical agents with the cytokinesis-block micronucleus cytome assay.
Humans Micronuclei, Chromosome-Defective Micronucleus Tests Mutagens Abstract: In order to evaluate the applicability of the cytokinesis-block micronucleus cytome assay in routine mutagenicity testing we ...