Search results - 146 results

Advancing the Replacement of animal testing in Toxicology via the RE-Place platform

RE-Place replacement Toxicology Service:  Évaluation des risques et de l'impact sur la santé Risico- en gezondheidsimpactevaluatie Risk and health impact assessment Risques chimiques et physiques pour ...

Physicochemical characterization and genotoxicity assessment of nanomaterials using new approach methodologies

BelTox, Issue The Belgian Society of Toxicology and Ecotoxicology, Ghent, Belgium (2024) Keywords: Copper Oxides Feed Additive food additive Food Sector genotoxicity Iron Oxides and Hydroxides Nanoparticles ...

Determination of 16 Hydroxyanthracene Derivatives in Food Supplements Using LC-MS/MS: Method Development and Application.

the European Commission prohibited a number of HAD s due to toxicological concerns. These HAD s included aloin (aloin A and aloin B), aloe-emodin, emodin, and danthron. Most of the currently available ...

VERMEER FCM: A tool integrating exposure and hazard modelling for chemicals migrating from food contact materials.

with Regulation (EU) No 10/2011 for plastic FCM. Overall, the tool consists of three modules that allow (i) to model the migration of chemicals into food, (ii) to predict toxicological endpoints relevant ...

Chemical Characterization of Feminine Intimate Products an Extractables & Leachables Investigation

conditions to identify all chemical constituents (extractables); (2) prioritizing these chemicals based on regulatory hazard information, supplemented by in silico toxicological data; and (3) performing ...

Safety assessment of the substances 'wax, rice bran, oxidised' and 'wax, rice bran, oxidised, calcium salt' for use in food contact materials.

result in exposures below (for aqueous food) and above (for fatty food) the threshold of toxicological concern for genotoxic carcinogens. Therefore, the FCM Panel concluded that the substances are not of ...

A validation methodology for size and shape measurement of nanoplastics by transmission electron microscopy

characterizing NP s proves to be challenging, especially within complex matrices [2]. A comprehensive physicochemical characterization is however imperative, especially for evaluating their potential toxicological ...

Towards a more effective REACH legislation in protecting human health.

is required. Fast toxicology battery testing and toxicokinetic testing could improve speed of decision-making. Hereby, several improvements have been proposed that could improve the current REACH ...

Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health.

data sets are available for altersetin (ALS), altenuene (ALT), and tentoxin (TEN). The occurrence and toxicological relevance of perylene quinone-based Alternaria toxins still remain to be fully ...

A preliminary estimate of the environmental burden of disease associated with exposure to pyrethroid insecticides and ADHD in Europe based on human biomonitoring

children compared to adults. Epidemiological, toxicological, and mechanistic studies raise concerns for potential human health effects, particularly, behavioral effects such as attention deficit ...

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